The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2013
Filed:
Jun. 09, 2008
Lars A. Solli, Klokkarstua, NO;
Anja Gulliksen, Klokkarstua, NO;
Frank Karlsen, Klokkarstua, NL;
Tobias Baier, Mainz, DE;
Rainer Gransee, Mainz, DE;
Thomas Hansen-hagge, Mainz, DE;
Klaus Stefan Drese, Mainz, DE;
Liv Furuberg, Oslo, NO;
Lars A. Solli, Klokkarstua, NO;
Anja Gulliksen, Klokkarstua, NO;
Frank Karlsen, Klokkarstua, NL;
Tobias Baier, Mainz, DE;
Rainer Gransee, Mainz, DE;
Thomas Hansen-Hagge, Mainz, DE;
Klaus Stefan Drese, Mainz, DE;
Liv Furuberg, Oslo, NO;
Norchip A/S, Klokkarstua, NO;
Abstract
The present invention provides an integrated lab-on-a-chip device for carrying out a nucleic acid extraction process on a fluid sample containing cells and/or particles, the device comprising: (a) a sample inlet () for loading of a fluid sample, (b) a lysis unit () for lysis of cells and/or particles present in the fluid sample, (c) a reservoir of lysis fluid () for the lysis unit, (d) a nucleic acid extraction unit () downstream of the lysis unit, and (e) reservoirs of first washing buffer and eluant fluid () for the nucleic acid extraction unit, wherein the device further comprises (f) a mixing unit () downstream of the nucleic acid extraction unit, and (g) a source of mixing fluid () for the mixing unit. The reservoirs of lysis fluid, first washing buffer and eluant fluid may be provided parallel to one anther so that they may be actuated by a single pump.