The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 26, 2013

Filed:

Dec. 28, 2006
Applicants:

Simone R. Oliveira, New Brighton, MN (US);

Randy R. Simonson, Worthington, MN (US);

Jonathan D. Mahlberg, Worthington, MN (US);

Mark D. Titus, Jackson, MN (US);

Tracy A. Oleson, Lake Park, WI (US);

Inventors:

Simone R. Oliveira, New Brighton, MN (US);

Randy R. Simonson, Worthington, MN (US);

Jonathan D. Mahlberg, Worthington, MN (US);

Mark D. Titus, Jackson, MN (US);

Tracy A. Oleson, Lake Park, WI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/102 (2006.01); A61K 48/00 (2006.01); A01N 63/00 (2006.01); A01N 65/00 (2009.01);
U.S. Cl.
CPC ...
Abstract

The present invention is a culture of cells ofexhibiting attenuated pathogenicity and capable of triggering a protective immune response when administered to pigs as a live vaccine. The present invention is also a method of preparing the cell culture, a method of preparing a vaccine from the cell culture, and a live vaccine based on the cell culture. The cell culture was modified from a pathogenic parent strain by MNNG mutagenesis and was selected by complete dependence on streptomycin for growth.


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