The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2013
Filed:
Mar. 13, 2008
Klaus Pfizenmaier, Tiefenbronn, DE;
Peter Scheurich, Stuttgart, DE;
Roland Kontermann, Ebsdorfergrund, DE;
Sabine Münkel, Gärtringen, DE;
Klaus Pfizenmaier, Tiefenbronn, DE;
Peter Scheurich, Stuttgart, DE;
Roland Kontermann, Ebsdorfergrund, DE;
Sabine Münkel, Gärtringen, DE;
Universitaet Stuttgart, , DE;
Abstract
The present invention relates to a ligand, which specifically binds to human tumor necrosis factor type 1 receptor (huTNFR1). The ligand includes one or more amino acid sequences of human origin capable of reducing the immunogenic response of the ligand in humans and one or more amino acid sequences capable of selectively binding to huTNFR1. The present invention also relates to a nucleic acid sequence encoding the ligand and to a pharmaceutical composition for the treatment of disorders related to huTNFR1.