The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 26, 2013
Filed:
May. 17, 2010
Applicants:
Anthony O. Caggiano, Larchmont, NY (US);
Andrea Vecchione, Mt. Vernon, NY (US);
Jennifer Iaci, Boonton, NJ (US);
Inventors:
Anthony O. Caggiano, Larchmont, NY (US);
Andrea Vecchione, Mt. Vernon, NY (US);
Jennifer Iaci, Boonton, NJ (US);
Assignee:
Acorda Therapeutics, Inc., Ardsley, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/46 (2006.01); C12N 9/88 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01); A61M 37/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to protein and nucleic acid mutants of chondroitinase ABCI. Such chondroitinase ABCI mutant enzymes exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.