The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2013

Filed:

Jun. 04, 2010
Applicants:

Roger A. Sabbadini, Lakeside, CA (US);

Tom Huxford, San Diego, CA (US);

Jonathan Michael Wojciak, Encinitas, CA (US);

Inventors:

Roger A. Sabbadini, Lakeside, CA (US);

Tom Huxford, San Diego, CA (US);

Jonathan Michael Wojciak, Encinitas, CA (US);

Assignee:

Lpath, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/44 (2006.01); G06G 7/60 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for designing optimized antibodies, including optimized humainized or human antibodies, to target bioactive lipids are provided. These methods may be performed in silico and may be intended to enhance binding affinity of an antibody to its original target lipid, and/or to alter binding specificity. Antibodies produced by these methods are also provided, as are methods for using them.


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