The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2013
Filed:
Jul. 20, 2011
Applicants:
Laurence M. Harwood, Berkshire, GB;
Ran Yan, Berkshire, GB;
Inventors:
Laurence M. Harwood, Berkshire, GB;
Ran Yan, Berkshire, GB;
Assignee:
University of Reading, Berkshire, Reading, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/64 (2006.01); C07K 5/08 (2006.01); C07K 5/06 (2006.01); C07K 1/06 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process comprising substitution of an acceptor molecule comprising a group —XC(O)— wherein X is O, S, or NR, where Ris Calkyl, Caryl or hydrogen, with a nucleophile, wherein the acceptor molecule is cyclised such that said nucleophilic substitution at —XC(O)— occurs without racemization, is provided. This process has particular application for the production of a peptide by extension from the activated carboxy-terminus of an acyl amino acid residue without epimerization.