The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2013

Filed:

Oct. 27, 2008
Applicants:

Gui-bai Liang, Scotch Plains, NJ (US);

Xibin Liao, Edison, NJ (US);

Weiguo Liu, Princeton, NJ (US);

Paul E. Finke, Milltown, NJ (US);

Dooseop Kim, Westfield, NJ (US);

Lihu Yang, Edison, NJ (US);

Songnian Lin, Monroe, NJ (US);

Inventors:

Gui-Bai Liang, Scotch Plains, NJ (US);

Xibin Liao, Edison, NJ (US);

Weiguo Liu, Princeton, NJ (US);

Paul E. Finke, Milltown, NJ (US);

Dooseop Kim, Westfield, NJ (US);

Lihu Yang, Edison, NJ (US);

Songnian Lin, Monroe, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/38 (2006.01); A61K 31/34 (2006.01); C07D 305/00 (2006.01); C07C 62/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Tricyclic compounds containing a cyclopropanecarboxylic acid fused to a bicyclic ring, including pharmaceutically acceptable salts, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.


Find Patent Forward Citations

Loading…