The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2013
Filed:
Nov. 06, 2007
Ivan Spasojevic, Durham, NC (US);
Michael O. Colvin, Chapel Hill, NC (US);
Ines Batinic-haberle, Durham, NC (US);
Susan M. Ludeman, Delmar, NY (US);
Michael P. Gamcsik, Chapel Hill, NC (US);
Ivan Spasojevic, Durham, NC (US);
Michael O. Colvin, Chapel Hill, NC (US);
Ines Batinic-Haberle, Durham, NC (US);
Susan M. Ludeman, Delmar, NY (US);
Michael P. Gamcsik, Chapel Hill, NC (US);
Duke University, Durham, NC (US);
Abstract
The present invention provides a method of hydroxylating or oxidizing a compound of interest in a subject (e.g., a cytotoxic oxazaphosphorine prodrug), by administering the compound of interest to the subject; and concurrently administering the subject a metalloporphyrin in an amount effective to hydroxylate or oxidize the compound of interest in the subject.