The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2013
Filed:
May. 05, 2008
Michele A. Cleary, Jamison, PA (US);
Aimee L. Jackson, Carlsbad, CA (US);
Peter S. Linsley, Encinitas, CA (US);
Julja Burchard, San Francisco, CA (US);
Lee P. Lim, San Francisco, CA (US);
Jill F. Magnus, Seattle, WA (US);
Lin He, Berkeley, CA (US);
Xingyue He, Cambridge, MA (US);
Scott W. Lowe, Cold Spring Harbor, NY (US);
Gregory J. Hannon, Hungtington, NY (US);
Michele A. Cleary, Jamison, PA (US);
Aimee L. Jackson, Carlsbad, CA (US);
Peter S. Linsley, Encinitas, CA (US);
Julja Burchard, San Francisco, CA (US);
Lee P. Lim, San Francisco, CA (US);
Jill F. Magnus, Seattle, WA (US);
Lin He, Berkeley, CA (US);
Xingyue He, Cambridge, MA (US);
Scott W. Lowe, Cold Spring Harbor, NY (US);
Gregory J. Hannon, Hungtington, NY (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
In one aspect, the invention generally relates to use of miR-34 as a biomarker to estimate TP53 function in a cell. In another aspect, the invention generally relates to multiple uses of miR-34 and siRNAs functionally and structurally related to miR-34 for the treatment of cancer.