The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2013
Filed:
May. 25, 2005
Gernot Achatz, Salzburg, AT;
Michael Huhn, Leverkusen, DE;
Rainer Fischer, Monschau, DE;
Fatima Ferreira, Salzburg, AT;
Elke Luger, Marchtrenk, AT;
Michael Stöcker, Aachen, DE;
Stefan Barth, Roetgen, DE;
Torsten Klockenbring, Bonn, DE;
Gernot Achatz, Salzburg, AT;
Michael Huhn, Leverkusen, DE;
Rainer Fischer, Monschau, DE;
Fatima Ferreira, Salzburg, AT;
Elke Luger, Marchtrenk, AT;
Michael Stöcker, Aachen, DE;
Stefan Barth, Roetgen, DE;
Torsten Klockenbring, Bonn, DE;
Abstract
A process is disclosed which enables the establishing of comprehensive immunoglobulin-specific reaction profiles of subjects with disorders of the immune function by the individual V gene repertoire of Ig-expressing B cells. The process comprises the isolation of B cells from body fluids, the isolation of individual B cells and their genetic material, the amplification of nucleic acids coding the variable regions of an antibody expressed by a B cell, the recombinant preparation of antibodies by expressing the amplificates, and the determination of the binding capability of the recombinant antibody to antigens.