The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 19, 2013
Filed:
Jan. 12, 2011
Lauren O. Bakaletz, Hilliard, OH (US);
Robert S. Munson, Jr., Hilliard, OH (US);
Lauren O. Bakaletz, Hilliard, OH (US);
Robert S. Munson, Jr., Hilliard, OH (US);
Nationwide Children's Hospital, Inc., Columbus, OH (US);
Abstract
The invention described herein relates to a() regulon encoding type IV pili. In particular, the invention relates to type pili from nontypeable(NTHi) and fromstrains a, b, c, e and f. The invention provides isolatedpilus polynucleotides and polypeptides encoded by the polynucleotides as well as polynucleotides and polypeptides encoded by the polynucleotides involved in the assembly/disassembly of the structure. The invention also relates to uses of these polynucleotides and/or polypeptides including methods for eliciting an immune response toand methods of treating and preventingrelated pathological conditions.