The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2013

Filed:

Nov. 05, 2010
Applicants:

Fang Fang, Rancho Santa Fe, CA (US);

David Wurtman, San Diego, CA (US);

Ron Moss, Encinitas, CA (US);

Michael P. Malakhov, San Francisco, CA (US);

Inventors:

Fang Fang, Rancho Santa Fe, CA (US);

David Wurtman, San Diego, CA (US);

Ron Moss, Encinitas, CA (US);

Michael P. Malakhov, San Francisco, CA (US);

Assignee:

NexBio, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a method of reducing the quanitity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quanitity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.


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