The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 19, 2013

Filed:

May. 29, 2009
Applicants:

Tibor Bakács, Budapest, HU;

Imre Kövesdi, Rockville, MD (US);

Vilmos Palya, Budapest, HU;

Inventors:

Tibor Bakács, Budapest, HU;

Imre Kövesdi, Rockville, MD (US);

Vilmos Palya, Budapest, HU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/04 (2006.01); A61K 48/00 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses a novel apathogenic viral strain useful in the treatment of viral hepatitis infections. The preferred viral strain of Infectious Bursal Disease Virus (IBDV) is specifically characterized in terms of structure and biological activities. The invention also provides recombinant IBDV viral vectors for the inclusion of exogenous nucleic acid sequences enhancing the viral replication inhibitory effect of the virus of the invention. Preferably, the viral vector comprises a nucleic acid sequence encoding a cytokine. A method of treating viral hepatitis in a host comprising administering an anti-hepatitis effective amount of the IBDV strain of the present invention also provided.


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