The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2013
Filed:
Oct. 20, 2011
Eddy Jean Edgard Freyne, Rumst, BE;
Marc Willems, Vosselaar, BE;
Werner Constant Johan Embrechts, Beerse, BE;
Kristof Van Emelen, Sint-Niklaas, BE;
Sven Franciscus Anna Van Brandt, Nijlen, BE;
Frederik Jan Rita Rombouts, Antwerp, BE;
Eddy Jean Edgard Freyne, Rumst, BE;
Marc Willems, Vosselaar, BE;
Werner Constant Johan Embrechts, Beerse, BE;
Kristof Van Emelen, Sint-Niklaas, BE;
Sven Franciscus Anna Van Brandt, Nijlen, BE;
Frederik Jan Rita Rombouts, Antwerp, BE;
Janssen Pharmaceutica N.V., Beerse, BE;
Abstract
The present invention is drawn to intermediates relating to 2,4 (4,6) pyrimidine derived macrocycles, pharmaceutical compositions thereof, and methods of making said compounds. The compounds disclosed herein are inhibitors of EGF receptor tyrosine kinases and are useful for treating cell proliferative disorders, including atherosclerosis, restenosis, and cancer.