The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8394936 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 12, 2013

Filed:

May. 18, 2006
Applicants:

Jason Trama, Burlington, NJ (US);

Eli Mordechai, Robbinsville, NJ (US);

Martin E. Adelson, Hillsborough, NJ (US);

Inventors:

Jason Trama, Burlington, NJ (US);

Eli Mordechai, Robbinsville, NJ (US);

Martin E. Adelson, Hillsborough, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are methods and compositions for conducting assays of samples utilizing polymerase chain reactions ('PCRs') in the detection of serotypes ofcapable of causing lymphogranuloma venereum ('LGV'). These assays take advantage of a deletion occurring in the cytotoxin gene locus specific to the L I, L II, and L serotypes. Each of these assays employs a first primer having a nucleotide sequence flanking one side of the deletion point and a second primer having a nucleotide sequence flanking the other side of the deletion point, wherein the first primer and the second primer are capable of hybridizing respectively to the plus strand and the minus strand of the genome ofduring the PCR. Synthesis during the PCR of a sequence-specific amplicon containing this deletion point indicates that the sample contains nucleic acid specific to an LGV-causing serotype of


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