The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2013

Filed:

Sep. 17, 2009
Applicants:

Danilo Mirizzi, Milan, IT;

Giovanni Cervi, Como, IT;

Matteo D'anello, Novate Milanese, IT;

Gianluca Mariano Enrico Papeo, Cernusco Lombardone, IT;

Ron Ferguson, Scotch Plains, NJ (US);

Francesco Casuscelli, Dairago, IT;

Inventors:

Danilo Mirizzi, Milan, IT;

Giovanni Cervi, Como, IT;

Matteo D'Anello, Novate Milanese, IT;

Gianluca Mariano Enrico Papeo, Cernusco Lombardone, IT;

Ron Ferguson, Scotch Plains, NJ (US);

Francesco Casuscelli, Dairago, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds which are 4,7-disubstituted derivatives of 3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one compounds with the formula or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.


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