The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 12, 2013

Filed:

Feb. 27, 2009
Applicants:

Kateri A. Ahrendt, Boulder, CO (US);

Alexandre J. Buckmelter, Boulder, CO (US);

Jason DE Meese, Boulder, CO (US);

Jonas Grina, Boulder, CO (US);

Joshua D. Hansen, Boulder, CO (US);

Ellen R. Laird, Boulder, CO (US);

Paul Lunghofer, Boulder, CO (US);

David Moreno, Boulder, CO (US);

Brad Newhouse, Boulder, CO (US);

LI Ren, Boulder, CO (US);

Jeongbeob Seo, Boulder, CO (US);

Hongqi Tian, Boulder, CO (US);

Steven Mark Wenglowsky, Boulder, CO (US);

Bainian Feng, South San Francisco, CA (US);

Janet Gunzner, South San Francisco, CA (US);

Kim Malesky, South San Francisco, CA (US);

Simon Mathieu, South San Francisco, CA (US);

Joachim Rudolph, South San Francisco, CA (US);

Zhaoyang Wen, South San Francisco, CA (US);

Wendy B. Young, South San Francisco, CA (US);

Inventors:

Kateri A. Ahrendt, Boulder, CO (US);

Alexandre J. Buckmelter, Boulder, CO (US);

Jason De Meese, Boulder, CO (US);

Jonas Grina, Boulder, CO (US);

Joshua D. Hansen, Boulder, CO (US);

Ellen R. Laird, Boulder, CO (US);

Paul Lunghofer, Boulder, CO (US);

David Moreno, Boulder, CO (US);

Brad Newhouse, Boulder, CO (US);

Li Ren, Boulder, CO (US);

Jeongbeob Seo, Boulder, CO (US);

Hongqi Tian, Boulder, CO (US);

Steven Mark Wenglowsky, Boulder, CO (US);

Bainian Feng, South San Francisco, CA (US);

Janet Gunzner, South San Francisco, CA (US);

Kim Malesky, South San Francisco, CA (US);

Simon Mathieu, South San Francisco, CA (US);

Joachim Rudolph, South San Francisco, CA (US);

Zhaoyang Wen, South San Francisco, CA (US);

Wendy B. Young, South San Francisco, CA (US);

Assignees:

Array BioPharma Inc., Boulder, CO (US);

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/44 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.


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