The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2013
Filed:
Apr. 14, 2006
Daniel D. Von Hoff, Scottsdale, AZ (US);
Haiyong Han, Chandler, AZ (US);
Hong Wang, East Brunswick, NJ (US);
Gary A. Flynn, Oro Valley, AZ (US);
Daniel D. Von Hoff, Scottsdale, AZ (US);
Haiyong Han, Chandler, AZ (US);
Hong Wang, East Brunswick, NJ (US);
Gary A. Flynn, Oro Valley, AZ (US);
The Translation Genomics Research Institute, Phoenix, AZ (US);
The Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);
Abstract
This invention is directed to methods for screening and identification of compounds capable of selectively eliminating cancer cells with specific loss-of-function alterations, including but not limited to mutations, deletions, hypermethylations, and other types of gene silencing. This invention is also directed to novel compounds that selectively eliminate cancer cells with specific loss-of-function alterations. Furthermore, this invention is directed to methods for production and therapeutic use of compounds that selectively eliminate cancer cells with specific loss-of-function alterations.