The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2013
Filed:
Jun. 07, 2010
Stevan B. Jovanovich, Livermore, CA (US);
William D. Nielsen, San Jose, CA (US);
David S. Cohen, San Bruno, CA (US);
Michael Recknor, Oakland, CA (US);
Mattias Vangbo, Fremont, CA (US);
Ezra Van Gelder, Palo Alto, CA (US);
Lars Majlof, San Jose, CA (US);
Omar El-sissi, Fremont, CA (US);
Stevan B. Jovanovich, Livermore, CA (US);
William D. Nielsen, San Jose, CA (US);
David S. Cohen, San Bruno, CA (US);
Michael Recknor, Oakland, CA (US);
Mattias Vangbo, Fremont, CA (US);
Ezra Van Gelder, Palo Alto, CA (US);
Lars Majlof, San Jose, CA (US);
Omar El-Sissi, Fremont, CA (US);
IntegenX Inc., Pleasanton, CA (US);
Abstract
The invention provides a system that can process a raw biological sample, perform a biochemical reaction and provide an analysis readout. For example, the system can extract DNA from a swab, amplify STR loci from the DNA, and analyze the amplified loci and STR markers in the sample. The system integrates these functions by using microfluidic components to connect what can be macrofluidic functions. In one embodiment the system includes a sample purification module, a reaction module, a post-reaction clean-up module, a capillary electrophoresis module and a computer. In certain embodiments, the system includes a disposable cartridge for performing analyte capture. The cartridge can comprise a fluidic manifold having macrofluidic chambers mated with microfluidic chips that route the liquids between chambers. The system fits within an enclosure of no more than 10 ft. and can be a closed, portable, and/or a battery operated system. The system can be used to go from raw sample to analysis in less than 4 hours.