The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 12, 2013
Filed:
Aug. 31, 2007
You Han Bae, Salt Lake City, UT (US);
Eun Seong Lee, Salt Lake City, UT (US);
Dongin Kim, Salt Lake City, UT (US);
Yu Seok Youn, Salt Lake City, UT (US);
Kyung Taek OH, Salt Lake City, UT (US);
You Han Bae, Salt Lake City, UT (US);
Eun Seong Lee, Salt Lake City, UT (US);
Dongin Kim, Salt Lake City, UT (US);
Yu Seok Youn, Salt Lake City, UT (US);
Kyung Taek Oh, Salt Lake City, UT (US);
University of Utah Research Foundation, Salt Lake City, UT (US);
Abstract
A drug delivery vehicle for targeted delivery of a drug mimics viral properties of size, capsid-like protein capsule, cell-specific entry, toxin release, destruction of infected cells, and migration to neighboring cells. This vehicle, termed a virogel, contains a hydrophobic polymeric core, a hydrophilic inner shell, a hydrophilic outer shell, and a ligand. An illustrative drug-loaded virogel includes poly(L-histidine-co-phenylalanine) as the core, doxorubicin loaded in the core, polyethylene glycol as the inner shell, bovine serum albumin as the outer shell, and folic acid as the ligand.