The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2013
Filed:
Aug. 26, 2008
Kevin J. Tracey, Old Greenwich, CT (US);
Howland Shaw Warren, Cambridge, MA (US);
Christine N. Metz, Great Neck, NY (US);
Kevin J. Tracey, Old Greenwich, CT (US);
Howland Shaw Warren, Cambridge, MA (US);
Christine N. Metz, Great Neck, NY (US);
The Feinstein Institute for Medical Research, Manhasset, NY (US);
Abstract
Described herein are methods, devices and systems for inhibition of granulocyte activation by appropriate stimulation of the vagus nerve. Methods of treating granulocyte-mediated disorders (including inflammatory disorders) by stimulating the vagus nerve to inhibit granulocyte activation (particularly neutrophil activation) are also described. Appropriate stimulation may be very low levels of stimulation, including stimulation that does not result in desensitization. The level of granulocyte activation may be detected and used to at least partially control stimulation.