The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2013
Filed:
May. 01, 2009
Leaf Huang, Durham, NC (US);
Yunching Chen, Boston, MA (US);
Joyeeta Sen, West Bengal, IN;
Surendar Reddy Bathula, Tarnaka Hyderabad, IN;
Sumio Chono, Hokkaido, JP;
Shyh-dar LI, Toronto, CA;
Michael Hackett, Chapel Hill, NC (US);
Leaf Huang, Durham, NC (US);
Yunching Chen, Boston, MA (US);
Joyeeta Sen, West Bengal, IN;
Surendar Reddy Bathula, Tarnaka Hyderabad, IN;
Sumio Chono, Hokkaido, JP;
Shyh-Dar Li, Toronto, CA;
Michael Hackett, Chapel Hill, NC (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Abstract
Provided herein are novel cationic lipids, compositions comprising the cationic lipids, and methods of using the cationic lipids. In some claims, the cationic lipids have cytotoxic activity and can be used alone or in combination with a cytotoxic bioactive compound to kill a cell. In some of these claims, the cationic lipid enhances the cytotoxic activity of the cytotoxic bioactive compound. Methods for treating a subject afflicted with a disease or unwanted condition are provided, wherein the method comprises administering a delivery system comprising a novel cationic lipid to the subject. The invention further provides methods for making delivery systems comprising the novel cationic lipids of the invention.