The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2013

Filed:

Jan. 17, 2007
Applicants:

Yung Hou Wong, Hong Kong, CN;

Maurice Kwok Chung Ho, Hong Kong, CN;

Yueqing HU, Hong Kong, CN;

David Charles New, Hong Kong, CN;

Xixin He, Honolulu, HI (US);

Haihong Pang, Hong Kong, CN;

Inventors:

Yung Hou Wong, Hong Kong, CN;

Maurice Kwok Chung Ho, Hong Kong, CN;

Yueqing Hu, Hong Kong, CN;

David Charles New, Hong Kong, CN;

Xixin He, Honolulu, HI (US);

Haihong Pang, Hong Kong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); C07D 217/23 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of treating, preventing, or ameliorating a pathological condition associated with a melatonin receptor in a mammal by using a pharmaceutical composition containing a compound of formula (I) as a ligand interacting with the melatonin receptor, R, R, R, Rand Rare independently H, halo, alkyloxyl, alkyl or hydroxyl, provided that one of R, R, Rand Ris X—(CH)—R; Ris alkyl or arylalkyl; Ris H or alkyl; X is a bond, O, S, SO, SO, CO or NH; n=-; Ris alkenyl, substituted or unsubstituted aryl, NRR, or OR; Ris H, substituted or unsubstituted arylmethyl, or alkenyl; and Ris H or alkyl.


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