The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 05, 2013

Filed:

Feb. 13, 2008
Applicants:

Himanshu Jain, Bethlehem, PA (US);

Hassan Mohamady Mohamed Moawad, Bethlehem, PA (US);

Inventors:

Himanshu Jain, Bethlehem, PA (US);

Hassan Mohamady Mohamed Moawad, Bethlehem, PA (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 59/26 (2006.01); A61K 33/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

The methods and materials described herein provide novel and simple procedures for the preparation of nano/macroporous glasses, in which the pore structure is characterized by interconnected pores of, e.g. both hundreds of micrometers and several to tens of nanometers in size. Such materials may be used for enhanced bone regeneration, bioscaffolds, drug delivery devices, and filtration media, among other uses. For example, silica-based bone tissue scaffolds are made with a controlled nano/macroporosity, which enhances bone regeneration performance. Also provided herein are new biocompatible CaO—NaO—PO—SiOglasses prepared by thermal melt-quench methods that result in spinodal phase separation and crystallization of phases at very different length scales. Selective chemical leaching of these phases causes formation of interconnected multi-modal porosity, with pore sizes ranging from several nanometers to tens of micrometers.


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