The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 05, 2013
Filed:
Sep. 23, 2011
David S. F. Young, Toronto, CA;
Daad Sayegh, Mississauga, CA;
Sheung Tat Fan, Hong Kong, CN;
Ronnie Tung Ping Poon, Hong Kong, CN;
Terence Kin Wah Lee, Hong Kong, CN;
David S. F. Young, Toronto, CA;
Daad Sayegh, Mississauga, CA;
Sheung Tat Fan, Hong Kong, CN;
Ronnie Tung Ping Poon, Hong Kong, CN;
Terence Kin Wah Lee, Hong Kong, CN;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of primary and metastatic human tumor cells; and most particularly to the use of an isolated monoclonal antibody or cancerous disease modifying antibodies (CDMAB) thereof, optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response in such human tumors, e.g. any primary or metastatic tumor sites which arise from hepatocytes. The invention further relates to binding assays which utilize the CDMAB of the instant invention.