The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2013
Filed:
Aug. 04, 2005
Ellen Baxter, Glenside, PA (US);
Francois Paul Bischoff, Vosselaar, BE;
Robert E. Boyd, Horsham, PA (US);
Mirielle Braeken, Vlimmeren, BE;
Steve Coats, Quakertown, PA (US);
Yifang Huang, Lansdale, PA (US);
Alfonzo D. Jordan, North Wales, PA (US);
Chi Luo, New Hope, PA (US);
Marc Hubert Mercken, Turnhout, BE;
Serge Maria Aloysius Pieters, AR Hulst, NL;
Allen B. Reitz, Lansdale, PA (US);
Charles H. Reynolds, Lansdale, PA (US);
Tina Morgan Ross, Royersford, PA (US);
Brett A. Tounge, Blue Bell, PA (US);
Mark J. Schulz, Skippack, PA (US);
Hans Louis Jos DE Winter, Schilde, BE;
Ellen Baxter, Glenside, PA (US);
Francois Paul Bischoff, Vosselaar, BE;
Robert E. Boyd, Horsham, PA (US);
Mirielle Braeken, Vlimmeren, BE;
Steve Coats, Quakertown, PA (US);
Yifang Huang, Lansdale, PA (US);
Alfonzo D. Jordan, North Wales, PA (US);
Chi Luo, New Hope, PA (US);
Marc Hubert Mercken, Turnhout, BE;
Serge Maria Aloysius Pieters, AR Hulst, NL;
Allen B. Reitz, Lansdale, PA (US);
Charles H. Reynolds, Lansdale, PA (US);
Tina Morgan Ross, Royersford, PA (US);
Brett A. Tounge, Blue Bell, PA (US);
Mark J. Schulz, Skippack, PA (US);
Hans Louis Jos De Winter, Schilde, BE;
Jansssen Pharmaceutica N.V., Beerse, BE;
Abstract
The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of β-secretase, also known as β-site cleaving enzyme and BACE.