The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 26, 2013
Filed:
Jun. 17, 2008
Ekambar Kandimalla, Southboro, MA (US);
Daqing Wang, Bedford, MA (US);
Yukui LI, Newton, MA (US);
Dong Yu, Westboro, MA (US);
Fugang Zhu, Bedford, MA (US);
Lakshmi Bhagat, Framingham, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Ekambar Kandimalla, Southboro, MA (US);
Daqing Wang, Bedford, MA (US);
Yukui Li, Newton, MA (US);
Dong Yu, Westboro, MA (US);
FuGang Zhu, Bedford, MA (US);
Lakshmi Bhagat, Framingham, MA (US);
Sudhir Agrawal, Shrewsbury, MA (US);
Idera Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The invention provides novel immune regulatory oligonucleotides (IRO) as antagonist of TLRs and methods of use thereof. These IROs have unique sequences that inhibit or suppress TLR-mediated signaling in response to a TLR ligand or TLR agonist. The methods may have use in the prevention and treatment of cancer, an autoimmune disorder, airway inflammation, inflammatory disorders, infectious disease, skin disorders, allergy, asthma or a disease caused by a pathogen.