The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2013

Filed:

Oct. 27, 2009
Applicants:

Hedi M Mattoussi, Tallahassee, FL (US);

Philip E Dawson, San Diego, CA (US);

Harry Tetsuo Uyeda, College Park, MD (US);

Igor L Medintz, Springfield, VA (US);

Johanna Scheinost, Oxford, GB;

Inventors:

Hedi M Mattoussi, Tallahassee, FL (US);

Philip E Dawson, San Diego, CA (US);

Harry Tetsuo Uyeda, College Park, MD (US);

Igor L Medintz, Springfield, VA (US);

Johanna Scheinost, Oxford, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for covalent attachment of peptides to luminescent quantum dots or other inorganic nanoparticles. The first step in the method involves functionalizing at least a portion of a surface of the quantum dot or nanoparticle with one or more materials having at least one reactive functional group therein. Subsequently, a peptide having a reactive functional group is reacted with at least some of the quantum dot or nanoparticle reactive functional groups to covalently bond at least some of the peptide to the quantum dots or nanoparticles. Modifications of the basic method are disclosed which provide methods allowing customized fabrication of quantum dots having a variety of different functional properties and combinations of functional properties. Also disclosed are quantum dots and nanoparticles made by the methods of the present invention.


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