The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2013

Filed:

Dec. 12, 2008
Applicants:

Jan Olof G. Karlsson, Trondheim, NO;

Tino Kurz, Linköping, SE;

Rolf Andersson, Vikingstad, SE;

Inventors:

Jan Olof G. Karlsson, Trondheim, NO;

Tino Kurz, Linköping, SE;

Rolf Andersson, Vikingstad, SE;

Assignee:

PledPharma AB, Stockholm, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/444 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compound of Formula I or a salt thereof for treating cancer, wherein X represents CH or N; Rrepresents hydrogen or —CHCOR; Rrepresents hydroxy, optionally hydroxylated alkoxy, amino or alkylamido; Rrepresents ZYR; Z represents a bond, or a Calkylene or oxoalkylene group optionally substituted by R; Y represents a bond, an oxygen atom or NR; Ris a hydrogen atom, COOR, an alkyl, alkenyl, cycloalkyl, aryl or aralkyl group optionally substituted by one or more selected from COOR, CONR, NR, OR, ═NR, ═O, OP(O)(OR)Rand OSOM; Ris hydroxy, an optionally hydroxylated, optionally alkoxylated alkyl or aminoalkyl group; Ris a hydrogen atom or an optionally hydroxylated, optionally alkoxylated alkyl group; M is a hydrogen atom or one equivalent of a physiologically tolerable cation; Rrepresents Calkylene, 1,2-cykloalkylene, or 1,2-arylene, optionally substituted with R; and Rrepresents hydrogen or Calkyl.


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