The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2013

Filed:

Feb. 14, 2008
Applicants:

Tomohiro Matsushima, Tsukuba, JP;

Shuji Shirotori, Tsukuba, JP;

Keiko Takahashi, Tsukuba, JP;

Atsushi Kamada, Tsukuba, JP;

Kazunori Wakasugi, Tsukuba, JP;

Takahisa Sakaguchi, Tsukuba, JP;

Inventors:

Tomohiro Matsushima, Tsukuba, JP;

Shuji Shirotori, Tsukuba, JP;

Keiko Takahashi, Tsukuba, JP;

Atsushi Kamada, Tsukuba, JP;

Kazunori Wakasugi, Tsukuba, JP;

Takahisa Sakaguchi, Tsukuba, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/4427 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides acid addition salts of the compounds represented by formula (1) or (2), or crystals thereof, and processes for preparing the same. The salts or crystals have HGFR inhibitory activity and excellent physical properties (solubility, safety, etc.) and are therefore useful as anti-tumor agents, angiogenesis inhibitors and inhibitors for metastasis for a various types of tumor.


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