The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 19, 2013

Filed:

Jan. 21, 2010
Applicants:

Rajinder Singh, Belmont, CA (US);

Huí LI, Santa Clara, CA (US);

Haoran Zhao, Foster City, CA (US);

Rao Kolluri, Foster City, CA (US);

Kin Tso, San Francisco, CA (US);

John Ramphal, Union City, CA (US);

Shihai Gu, Union City, CA (US);

Carlos Valdez, San Ramon, CA (US);

Jing Zhang, Mercer Island, WA (US);

Emily Stauffer, San Francisco, CA (US);

Matthew Duncton, San Bruno, CA (US);

Salvador Alvarez, Fremont, CA (US);

Inventors:

Rajinder Singh, Belmont, CA (US);

Huí Li, Santa Clara, CA (US);

Haoran Zhao, Foster City, CA (US);

Rao Kolluri, Foster City, CA (US);

Kin Tso, San Francisco, CA (US);

John Ramphal, Union City, CA (US);

Shihai Gu, Union City, CA (US);

Carlos Valdez, San Ramon, CA (US);

Jing Zhang, Mercer Island, WA (US);

Emily Stauffer, San Francisco, CA (US);

Matthew Duncton, San Bruno, CA (US);

Salvador Alvarez, Fremont, CA (US);

Assignee:

Rigel Pharmaceuticals Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61K 31/497 (2006.01); A61K 31/535 (2006.01); A61K 31/505 (2006.01); C07D 403/10 (2006.01); C07D 413/12 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

This disclosure concerns compounds which are useful as inhibitors of protein kinase C (PKC) and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC. This disclosure also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.


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