The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 19, 2013
Filed:
Jan. 06, 2011
Ming-derg Lai, Tainan, TW;
Shih-shien Huang, Tainan, TW;
Meng-chi Yen, Tainan, TW;
Chi-chen Lin, Taichung, TW;
Tzu-yang Weng, Tainan, TW;
Ming-Derg Lai, Tainan, TW;
Shih-Shien Huang, Tainan, TW;
Meng-Chi Yen, Tainan, TW;
Chi-Chen Lin, Taichung, TW;
Tzu-Yang Weng, Tainan, TW;
Abstract
The present invention relates to an RNAi compound and an expression plasmid for inhibiting expression of Thrombospondin-1, which comprises a target sequence selected from Thrombospondin-1 gene. The present invention also related to a pharmaceutical composition comprising the RNAi compound and applications thereof. The RNAi compound can reduce the expression of Thrombospondin-1 to activate immune responses. In addition, the present invention also disclosed that an RNAi compound targeted to Thrombospondin-1 gene can delay tumor progression.