The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 12, 2013

Filed:

Apr. 29, 2009
Applicants:

Robert E. Zipkin, Wynnewood, PA (US);

Sarah Spiegel, Richmond, VA (US);

Jeffrey Kroll Adams, Fort Washington, PA (US);

Inventors:

Robert E. Zipkin, Wynnewood, PA (US);

Sarah Spiegel, Richmond, VA (US);

Jeffrey Kroll Adams, Fort Washington, PA (US);

Assignee:

Enzo Therapeutics, Inc., Farmingdale, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/133 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are novel compositions which uniquely inhibit sphingosine kinase Type 1 (SphK1) and which are useful in a number of applications including killing or damaging cancer cells, inducing apoptosis, inhibiting growth, metastasis and development of chemoresistance in cancer cells, leukemia, increasing the effectiveness of anti-cancer agents, attenuating immune reactivity, inhibiting survival signaling in cancer cells, and reducing symptoms of multiple sclerosis.


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