The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 12, 2013
Filed:
Feb. 14, 2006
Applicants:
Cindy S. Orser, Lafayette, CO (US);
Tao Pan, Gaithersburg, MD (US);
Jasmeet Sethi, Germantown, MD (US);
Inventors:
Cindy S. Orser, Lafayette, CO (US);
Tao Pan, Gaithersburg, MD (US);
Jasmeet Sethi, Germantown, MD (US);
Assignee:
Adlyfe, Inc., Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 31/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides methods and kits for detecting conformationally altered proteins, such as prions or other proteins associated with disease states, in a sample. The methods comprise selectively capturing and separating complexes of peptide and conformationally altered protein from substances that interfere with detection of such complexes, and preferably amplification of the detection signal b addition of a second double-labeled peptide.