The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2013
Filed:
Apr. 27, 2010
Ying-zi Xu, Palo Alto, CA (US);
Shendong Yuan, San Ramon, CA (US);
David Wone, Newark, CA (US);
Andrei Konradi, Burlingame, CA (US);
Ying-zi Xu, Palo Alto, CA (US);
Shendong Yuan, San Ramon, CA (US);
David Wone, Newark, CA (US);
Andrei Konradi, Burlingame, CA (US);
Elan Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The present invention provides compounds that are alpha4 integrin antagonists having a structure according to the following formula: or a tautomer, mixture of tautomers, salt or solvate thereof, wherein Cy, ring A, m, n, p, R, R, R, R, Rand Rare defined in the specification. The invention further provides pharmaceutical compositions including the compounds of the invention as well as methods of making and using the compounds and compositions of the invention, e.g., in the treatment and prevention of various conditions and disorders, such as Crohn's disease and ulcerative colitis.