The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2013

Filed:

Nov. 30, 2009
Applicants:

Peter X. Wang, Clarkson Valley, MO (US);

Tao Jiang, St. Louis, MO (US);

Subo Liao, Ballwin, MO (US);

Erin Moore, Imperial, MO (US);

Inventors:

Peter X. Wang, Clarkson Valley, MO (US);

Tao Jiang, St. Louis, MO (US);

Subo Liao, Ballwin, MO (US);

Erin Moore, Imperial, MO (US);

Assignee:

Mallinckrodt LLC, Hazelwood, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/02 (2006.01); C07D 221/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present disclosure generally relates to a process for converting a fused, tricyclic compound to a fused, tetracyclic compound that includes a furan ring therein. More particularly, the present disclosure related to a process for preparing a hydrocodone compound, or a compound structurally related thereto, and in particular (+)-hydrocodone, by subjecting a structurally corresponding sinomenine starting compound to a super acid-assisted furan ring closure reaction.


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