The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2013
Filed:
May. 07, 2010
Jianxin Gao, Norton, MA (US);
James Luo, Quincy, MA (US);
Rong Zhou, Fullerton, CA (US);
Mary Ziping Luo, Diamond Bar, CA (US);
Jack Yongfeng Zhang, Diamond Bar, CA (US);
Jianxin Gao, Norton, MA (US);
James Luo, Quincy, MA (US);
Rong Zhou, Fullerton, CA (US);
Mary Ziping Luo, Diamond Bar, CA (US);
Jack Yongfeng Zhang, Diamond Bar, CA (US);
Amphastar Pharmaceuticals Inc., Rancho Cucamonga, CA (US);
Abstract
A stable suspension aerosol formulation of epinephrine is suitable for administration through inhalation comprising a therapeutically effective amount of epinephrine, hydrofluorocarbon propellant, co-solvent, surfactant, and antioxidant. The suspension aerosol formulation further comprises [pre-] pre-micronized epinephrine suspended in an alcohol/surfactant solution with hydrofluoroalkane propellant. The suspension formulation provides a highly efficient delivery of drug microparticles into the respirable region of patients' lungs and has the following advantages: lower dosage requirement, minimum alcohol content, with less impurities generated during storage, improved efficacy and safety, and exhibits no ozone depleting potential compared to a formulation containing chlorofluorocarbon.