The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2013

Filed:

May. 30, 2012
Applicants:

Amjad Ali, Freehold, NJ (US);

Michael Man-chu Lo, Edison, NJ (US);

Christopher Franklin, Quincy, MA (US);

Iyassu K. Sebhat, Jersey City, NJ (US);

Nicoletta Almirante, Milan, IT;

Silvia Stefanini, San Donato Milanese, IT;

Stefano Biondi, Pero, IT;

Ennio Ongini, Segrate, IT;

Inventors:

Amjad Ali, Freehold, NJ (US);

Michael Man-Chu Lo, Edison, NJ (US);

Christopher Franklin, Quincy, MA (US);

Iyassu K. Sebhat, Jersey City, NJ (US);

Nicoletta Almirante, Milan, IT;

Silvia Stefanini, San Donato Milanese, IT;

Stefano Biondi, Pero, IT;

Ennio Ongini, Segrate, IT;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); A61K 31/405 (2006.01); C07D 209/00 (2006.01); C07D 257/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound having the structure wherein R is, for example, Y is selected from the group consisting of 1) R5, 2) —C(R1R2) (C(R3R4))0-1Y1R5, and 3) —C(R1R2)—O—Y1R5; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-4 alkyl; R5 is; Y1 is selected from the group consisting of C(O)—O— and P(O)(OR6)—O—; and R6 is hydrogen or CH3, or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension.


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