The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2013
Filed:
Jun. 12, 2008
Jean-michel Vernier, Laguna Niguel, CA (US);
Samedy Ouk, Los Angeles, CA (US);
Martha A. DE LA Rosa, San Diego, CA (US);
Jean-Michel Vernier, Laguna Niguel, CA (US);
Samedy Ouk, Los Angeles, CA (US);
Martha A. De La Rosa, San Diego, CA (US);
Valeant Pharmaceuticals International, Aliso Viejo, CA (US);
Abstract
This invention provides potassium channel modulators which are compounds of formula I where at least one of W and Z is N;where the moiety is one of Groups A or B belowA where Ar is a 1,2-fused, six membered ring aromatic group, bearing substituents Rand Ras defined below, and containing zero or one ring nitrogen atom; and where other substituents are defined herein. The invention also provides a composition comprising a pharmaceutically acceptable carrier and at least one of the following: i) a pharmaceutically effective amount of a compound of formula I and ii) a pharmaceutically acceptable salt, ester, or prodrug thereof. The invention also provides a method of preventing or treating a disease or disorder which is affected by activities of potassium channels, comprising administering to a patient in need thereof a therapeutically effective amount of a compound of formula I or a salt, ester, or prodrug thereof.