The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2013

Filed:

Oct. 03, 2008
Applicants:

Pasit Phiasivongsa, Brentwood, CA (US);

Louis C. Sehl, Redwood City, CA (US);

William Dean Fuller, San Diego, CA (US);

Guy J. Laidig, Menlo Park, CA (US);

Inventors:

Pasit Phiasivongsa, Brentwood, CA (US);

Louis C. Sehl, Redwood City, CA (US);

William Dean Fuller, San Diego, CA (US);

Guy J. Laidig, Menlo Park, CA (US);

Assignee:

Onyx Therapeutics, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/07 (2006.01); C07K 1/00 (2006.01); C07K 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides.


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