The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2013
Filed:
Apr. 16, 2010
Applicant:
Gary Willard Reuther, Tampa, FL (US);
Inventor:
Gary Willard Reuther, Tampa, FL (US);
Assignee:
University of South Florida, Tampa, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01); C12N 5/07 (2010.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed in a method of detecting cancer using IL-27 receptors. IL27R is a cytokine receptor identified as a novel oncogene from an acute myeloid leukemia patient. It induces cancer-like properties when expressed in cells and can activate a protein that causes various myeloid cell disorders. The data show cytokine receptors play unappreciated roles in mediating activation of signaling pathways in circulatory system cancers. Also method of screening for novel oncogenes using a functional, approach is disclosed using cytokine-dependent cells to screen for transforming events.