The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2013
Filed:
Dec. 07, 2010
Jeremy Gray, San Francisco, CA (US);
Ronald L. Cicero, Palo Alto, CA (US);
Annette Grot, Cupertino, CA (US);
Natasha Popovich, Menlo Park, CA (US);
Stephen Dudek, San Francisco, CA (US);
Jeremy Gray, San Francisco, CA (US);
Ronald L. Cicero, Palo Alto, CA (US);
Annette Grot, Cupertino, CA (US);
Natasha Popovich, Menlo Park, CA (US);
Stephen Dudek, San Francisco, CA (US);
Pacific Biosciences of California, Inc., Menlo Park, CA (US);
Abstract
The application relates to methods for producing islands of functionality within nanoscale apertures. Islands of functionality can be produced by growing an aperture constriction layer from the walls, functionalizing the exposed base of the aperture, then removing the aperture constriction layer. The aperture constriction layer can be produced, for example, by anodically growing an oxide layer onto a cladding through which the aperture extends. The islands of functionality can be used to bind a single molecule of interest, such as an enzyme within the nanoscale aperture.