The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 05, 2013

Filed:

Sep. 27, 2007
Applicants:

Mario H. Skiadopoulos, Potomac, MD (US);

Brian R. Murphy, Bethesda, MD (US);

Peter L. Collins, Kensington, MD (US);

Inventors:

Mario H. Skiadopoulos, Potomac, MD (US);

Brian R. Murphy, Bethesda, MD (US);

Peter L. Collins, Kensington, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/155 (2006.01); C07H 23/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Recombinant human parainfluenza virus type 2 (HPIV2) viruses and related immunogenic compositions and methods are provided. The recombinant HPIV2 viruses, including HPIV2 chimeric and chimeric vector viruses, provided according to the invention are infectious and attenuated in permissive mammalian subjects, including humans, and are useful in immunogenic compositions for eliciting an immune responses against one or more PIVs, against one or more non-PIV pathogens, or against a PIV and a non-PIV pathogen. Also provided are isolated polynucleotide molecules and vectors incorporating a recombinant HPIV2 genome or antigenome.


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