The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2013
Filed:
Jul. 25, 2007
Satoji Takahashi, Yokkaichi, JP;
Mitsuhiko Kojima, Yokkaichi, JP;
Shouichi Kondou, Yokkaichi, JP;
Tatsuya Ishikawa, Yokkaichi, JP;
Yoshinori Ogawa, Kawagoe, JP;
Satoji Takahashi, Yokkaichi, JP;
Mitsuhiko Kojima, Yokkaichi, JP;
Shouichi Kondou, Yokkaichi, JP;
Tatsuya Ishikawa, Yokkaichi, JP;
Yoshinori Ogawa, Kawagoe, JP;
Ajinomoto Co., Inc., Tokyo, JP;
Abstract
The present invention relates to a method for producing a nucleoside derivative represented by formula (2), comprising the step of reducing a nucleoside of formula (1) in the presence of a noble metal catalyst comprising a carrier and a noble metal supported thereby, selected from the group consisting of (A) a homogeneously supported catalyst where the specific surface area of the noble metal is 95.0 m/g or more and the particle size of the noble metal is 4.3 nm or less, and (B) a surface-loaded catalyst where the specific surface area of the noble metal is 56.0 m/g or more and the particle size of the noble metal is 8.0 nm or less, wherein Ris hydrogen or a protective group, Ris NHor OH, Ris an acyl group, and X is a chlorine or bromine atom. According to the present invention, the yield can be made equal even when the amount of catalyst is smaller than that used for the conventional products.