The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2013
Filed:
Jun. 28, 2005
Applicants:
David Wallach, Rehovot, IL;
Elena Appel, Rishon Le Zion, IL;
Tanya Goncahrov, Ashkelon, IL;
Inventors:
Assignee:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/715 (2006.01); C07K 19/00 (2006.01); C12N 15/62 (2006.01); C12N 15/63 (2006.01); C12N 15/79 (2006.01); C12N 15/85 (2006.01); C12N 15/81 (2006.01); A61K 38/16 (2006.01); A61K 35/74 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides a chimeric protein capable of killing or modifying a cell expressing abnormally high levels of a ligand of a receptor of the TNF/NGF family, comprising the amino acid sequence of at least one polypeptide consisting of an extracellular portion of said receptor connected to an effector molecule. In addition the invention provides pharmaceutical compositions comprising said chimeric protein and use thereof.