The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2013
Filed:
May. 28, 2010
Richard Sedrani, Basel, CH;
Juergen Klaus Maibaum, Weil-Haltingen, DE;
Werner Breitenstein, Basel, CH;
Holger Sellner, Therwil, CH;
Claus Ehrhardt, Lorrach, DE;
Nils Ostermann, Binzen, DE;
Richard Sedrani, Basel, CH;
Juergen Klaus Maibaum, Weil-Haltingen, DE;
Werner Breitenstein, Basel, CH;
Holger Sellner, Therwil, CH;
Claus Ehrhardt, Lorrach, DE;
Nils Ostermann, Binzen, DE;
Novartis AG, Basel, CH;
Abstract
Compounds of the present invention having the formula exhibit inhibitory activity on the natural enzyme renin. Thus, compounds of formula (I) may be employed for the treatment of hypertension, atherosclerosis, unstable coronary syndrome, congestive heart failure, cardiac hypertrophy, cardiac fibrosis, cardiomyopathy postinfarction, unstable coronary syndrome, diastolic dysfunction, chronic kidney disease, hepatic fibrosis, complications resulting from diabetes, such as nephropathy, vasculopathy and neuropathy, diseases of the coronary vessels, restenosis following angioplasty, raised intra-ocular pressure, glaucoma, abnormal vascular growth, hyperaldosteronism, cognitive impairment, alzheimers, dementia, anxiety states and cognitive disorders.