The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2013
Filed:
Mar. 13, 2009
Raffaele Ingenito, Pomezia, IT;
Philip Jones, Pomezia, IT;
Laura Llauger Bufi, Pomezia, IT;
Jesus Maria Ontoria Ontoria, Pomezia, IT;
Rita Scarpelli, Pomezia, IT;
Raffaele Ingenito, Pomezia, IT;
Philip Jones, Pomezia, IT;
Laura Llauger Bufi, Pomezia, IT;
Jesus Maria Ontoria Ontoria, Pomezia, IT;
Rita Scarpelli, Pomezia, IT;
Abstract
The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinal damage, skin senescence and UV-induced skin damage, and as chemo- or radiosensitizers for cancer treatment.