The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2013

Filed:

Aug. 27, 2004
Applicants:

Wei Cheng, South San Francisco, CA (US);

Erick Wang CO, San Diego, CA (US);

Moon Hwan Kim, Palo Alto, CA (US);

Rhett Ronald Klein, Chicago, IL (US);

Donna T. Le, San Jose, CA (US);

Amy Lew, Milpitas, CA (US);

John M. Nuss, Danville, CA (US);

Wei Xu, Danville, CA (US);

William Bajjalieh, San Francisco, CA (US);

Inventors:

Wei Cheng, South San Francisco, CA (US);

Erick Wang Co, San Diego, CA (US);

Moon Hwan Kim, Palo Alto, CA (US);

Rhett Ronald Klein, Chicago, IL (US);

Donna T. Le, San Jose, CA (US);

Amy Lew, Milpitas, CA (US);

John M. Nuss, Danville, CA (US);

Wei Xu, Danville, CA (US);

William Bajjalieh, San Francisco, CA (US);

Assignee:

Exelixis, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/498 (2006.01); A61K 31/41 (2006.01); A61K 31/4192 (2006.01); A61K 31/505 (2006.01); A61K 31/4406 (2006.01); A61K 31/167 (2006.01); A61K 31/4196 (2006.01); C07D 257/04 (2006.01); C07D 249/06 (2006.01); C07D 213/30 (2006.01); C07D 239/26 (2006.01); C07D 249/08 (2006.01); C07D 241/42 (2006.01); C07C 233/15 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Even more specifically, the invention provides compounds for modulating c-Kit kinase activity and methods of treating diseases mediated by c-Kit activity utilizing the compounds and pharmaceutical compositions thereof.


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