The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2013

Filed:

Sep. 27, 2007
Applicants:

Edward P. Ingenito, North Quincy, MA (US);

Alexander Schwarz, Brookline, MA (US);

Larry W. Tsai, Boston, MA (US);

Inventors:

Edward P. Ingenito, North Quincy, MA (US);

Alexander Schwarz, Brookline, MA (US);

Larry W. Tsai, Boston, MA (US);

Assignee:

Aeris Therapeutics, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

One aspect of the invention relates to a hydrogel comprising a polymer comprising a plurality of pendent hydroxyl groups, a crosslinker, and a sclerosing agent. Another aspect of the invention relates to a method for reducing lung volume in a patient comprising the steps of advancing into a region of a patient's lung via said patient's trachea a multi-lumen catheter lumen through a bronchoscope; and co-administering, through the multi-lumen catheter, a first mixture comprising a first amount of a polymer containing a plurality of pendent hydroxyl groups; a second mixture comprising a second amount of a crosslinker; and a third mixture comprising a third amount of a sclerosing agent; thereby forming a hydrogel in said region. In certain embodiments, the compositions and methods described herein are intended for use in the treatment of patients with emphysema of the lung.


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