The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8361478 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 29, 2013

Filed:

Nov. 08, 2011
Applicants:

Maria G. Pau, Leiden, NL;

Lennart Holterman, Zoetermeer, NL;

Jorn Kaspers, Leiden, NL;

Antonius J. H. Stegmann, Katwijk, NL;

Inventors:

Maria G. Pau, Leiden, NL;

Lennart Holterman, Zoetermeer, NL;

Jorn Kaspers, Leiden, NL;

Antonius J. H. Stegmann, Katwijk, NL;

Assignee:

Crucell Holland B.V., Leiden, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 45/00 (2006.01); C12N 15/00 (2006.01); C12N 1/10 (2006.01); C07H 21/04 (2006.01); C07H 21/00 (2006.01); A01N 63/00 (2006.01); A01N 65/00 (2009.01);
U.S. Cl.
CPC ...
Abstract

Described are vaccines against malarial infections, which are based on recombinant viral vectors, such as alpha viruses, adenoviruses, or vaccinia viruses. The recombinant viral-based vaccines can be used to immunize against differentinfections, such as infections byor. Codon-optimized circumsporozoite genes are disclosed. Replication-defective adenoviruses may be used, derived from serotypes that encounter low titers of neutralizing antibodies. Also described is the use of different adenoviral serotypes that are administered to elicit a strong immune response, either in single vaccination set-ups or in prime-boost set-ups in which compositions based on different serotypes can be applied.


Find Patent Forward Citations

Pau, Maria. (2013). Recombinant viral-based malaria vaccines (U.S. Patent No. 8361478). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8361478

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…